There are two major referral hospitals in the Mid North Coast, Coffs Harbour Health Campus and Port Macquarie Base Hospital. University of NSW Medical Schools are located at both campuses and both facilities enjoy collaborative relationships with local universities and training organisations. Integrated cancer services providing complex services are available at both facilities in state of the art buildings adjacent to the main hospitals.

Coffs Harbour Health Campus

Coffs Harbour Health Campus was built in 2001 and is the major referral hospital for the Coffs Network of the Mid North Coast Local Health District.  It provides a broad range of specialist services to the residents of Coffs Harbour, Bellingen and Nambucca local government areas. With 292 beds, it provides the majority of specialist medical and surgical services for the Network.

These services include general medicine, surgery, day surgery, planned and emergency theatre service, coronary care (including coronary angiography unit), intensive care, canobstetrics, paediatrics, 24hour emergency department, oncology, palliative care, rehabilitation, stroke, acute renal dialysis, high dependency and mental health and an extensive range of outpatient clinics.

Allied health services, including occupational therapy, speech pathology, social work, physiotherapy, dietetics, radiology, pathology, and pharmacy, are an integral part of the organisation and contribute to the high level of patient care at Coffs Harbour Health Campus.

Port Macquarie Base Hospital

Port Macquarie Base Hospital is a major referral hospital for the Hastings Macleay Network. The hospital provides high level care for the population of Port Macquarie-Hastings and Kempsey LGAs, as well as for those of the Greater Taree and Great Lakes LGAs in Hunter New England LHD. With 195 beds, it provides the majority of specialist medical and surgical services for the Network.

These services include emergency operating theatres for all surgery, intensive care, coronary care and a range of diagnostic services. Port Macquarie Base Hospital also has an important role in providing regional services in fascio maxillary, vascular, urology and upper gastrointestinal surgery. A full range of community and allied health services are also based at the hospital.